- Protein first: Eat protein before carbs at every meal
- Small portions: You'll be full faster—don't force it
- Hydration: Sip water throughout the day (aim for 64+ oz)
- Bland is okay: If nauseous, stick to simple, gentle foods
- Don't skip: Even if not hungry, try to eat some protein
Week 1 Eating Principles
The first week on GLP-1 medication can be unpredictable. Your appetite may change dramatically—or not much at all yet. This meal plan is designed for flexibility:
| Goal | Target | Why |
|---|---|---|
| Protein | 60-80g minimum/day | Preserve muscle, maximize satiety |
| Fiber | 25-30g/day | Gut health, fullness (but may worsen GI symptoms—adjust) |
| Water | 64-80 oz/day | Prevent constipation, manage nausea |
| Calories | ~1200-1600 | Natural reduction from medication; don't force more |
Protein first, always. At every meal, eat your protein source before carbs or vegetables. This ensures you get adequate protein even when you can only eat a few bites.
Nausea-Friendly Foods
If you experience nausea (common days 2-4 after injection), these foods are typically well-tolerated:
- Plain Greek yogurt
- Scrambled eggs
- Chicken breast (plain, baked)
- Cottage cheese
- Protein smoothies (not too cold)
- Bone broth
- Saltine crackers (emergency)
- Ginger tea
- Bananas
Foods to Avoid Week 1
- Fried foods (slow digestion, worsen nausea)
- Very fatty meals
- Large portions
- Spicy foods
- Alcohol
- Carbonated beverages
- Very cold foods/drinks
The 7-Day Meal Plan
Protein: 20g
Protein: 28g
Protein: 28g
Protein: 12g
Day 1 Total: ~88g protein
Nausea may begin—portions smaller, foods gentler
Protein: 14g
Protein: 15g
Protein: 26g
Protein: 14g
Day 2 Total: ~69g protein
Protein: 28g
Protein: 25g
Protein: 24g
Protein: 12g
Day 3 Total: ~89g protein
Protein: 24g
Protein: 28g
Protein: 26g
Protein: 10g
Day 4 Total: ~88g protein
Protein: 16g
Protein: 26g
Protein: 28g
Protein: 10g
Day 5 Total: ~80g protein
Protein: 24g
Protein: 30g
Protein: 28g
Protein: 17g
Day 6 Total: ~99g protein
Protein: 21g
Protein: ~25g
Protein: 26g
Protein: 15g
Day 7 Total: ~87g protein
Week 1 Shopping List
Proteins
- Eggs (1 dozen)
- Greek yogurt (32 oz plain)
- Cottage cheese (16 oz)
- Chicken breasts (1.5 lbs)
- Salmon filets (12 oz)
- Shrimp (12 oz)
- Deli turkey & ham
- Ground turkey
- Canned tuna
- String cheese
- Protein powder
Produce
- Berries, bananas, apples, peaches
- Broccoli, carrots, zucchini, Brussels sprouts
- Mixed greens, romaine, spinach
- Cherry tomatoes, cucumbers
- Academy of Nutrition and Dietetics. Protein Requirements During Weight Loss. 2023.
- Obesity Medicine Association. Dietary Recommendations for Obesity Pharmacotherapy. 2024.
- Heymsfield SB, et al. Weight Loss Composition. Am J Clin Nutr. 2014.
- Novo Nordisk. Wegovy Patient Guide. 2024.
- Eli Lilly. Zepbound Patient Guide. 2024.
- Wharton S, et al. Nutrition and GLP-1 Therapy. Obesity. 2023.